Entity Details

Name SLC9A3R1
ID O14745
Role substrate
Enzymatic Domains
PDZ 1 14-94
PROSITE-ProRule
PDZ 2 154-234
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1SLC9A3R1Ser280LAEAALEsPRPALVRphosphorylation
down-regulates activity		20937695SIGNOR-278305
RPS6KA1SLC9A3R1Thr156ELRPRLCtMKKGPSGphosphorylation
up-regulates activity		26862730SIGNOR-278290
GRK6SLC9A3R1Ser290PALVRSAsSDTSEELphosphorylation
down-regulates activity		10446210SIGNOR-251214
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
SLC9A3R1
PSer280		phosphorylation
down-regulates
⊣		SLC9A3R120937695SIGNOR-278305
RPS6KA1phosphorylation
up-regulates
→
SLC9A3R1
PThr156		phosphorylation
up-regulates
→		SLC9A3R126862730SIGNOR-278290
GRK6phosphorylation
up-regulates
→
SLC9A3R1
PSer290		phosphorylation
down-regulates
⊣		SLC9A3R110446210SIGNOR-251214
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
down-regulates activity 		SLC9A3R1SIGNOR-278305
RPS6KA1phosphorylation
→
up-regulates activity 		SLC9A3R1SIGNOR-278290
GRK6phosphorylation
→
down-regulates activity 		SLC9A3R1SIGNOR-251214