Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
AKT	TERT	Ser824	AVRIRGKsYVQCQGI	phosphorylation up-regulates	10224060	SIGNOR-244357
AKT1	TERT	Ser824	AVRIRGKsYVQCQGI	phosphorylation up-regulates	10224060	SIGNOR-67317
DYRK2	TERT	–		phosphorylation down-regulates activity	23362280	SIGNOR-279611
AKT	TERT	Ser227	GARRRGGsASRSLPL	phosphorylation up-regulates	10224060	SIGNOR-244361
ABL1	TERT	–		phosphorylation down-regulates activity	10837221	SIGNOR-279354
AKT1	TERT	Ser227	GARRRGGsASRSLPL	phosphorylation up-regulates	10224060	SIGNOR-67313
SRC	TERT	Tyr707	QDPPPELyFVKVDVT	phosphorylation down-regulates	12808100	SIGNOR-102097
CDK1	TERT	Thr249	AAPEPERtPVGQGSW	phosphorylation up-regulates activity	32214089	SIGNOR-277517

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
AKT	phosphorylation up-regulates →	TERT PSer824	phosphorylation up-regulates →	TERT	10224060	SIGNOR-244357
AKT1	phosphorylation up-regulates →	TERT PSer824	phosphorylation up-regulates →	TERT	10224060	SIGNOR-67317
AKT	phosphorylation up-regulates →	TERT PSer227	phosphorylation up-regulates →	TERT	10224060	SIGNOR-244361
AKT1	phosphorylation up-regulates →	TERT PSer227	phosphorylation up-regulates →	TERT	10224060	SIGNOR-67313
SRC	phosphorylation up-regulates →	TERT PTyr707	phosphorylation down-regulates ⊣	TERT	12808100	SIGNOR-102097
CDK1	phosphorylation up-regulates →	TERT PThr249	phosphorylation up-regulates →	TERT	32214089	SIGNOR-277517

Regulator	Mechanism/Effect	Target	SIGNOR-ID
AKT	phosphorylation → up-regulates	TERT	SIGNOR-244357
AKT1	phosphorylation → up-regulates	TERT	SIGNOR-67317
DYRK2	phosphorylation → down-regulates activity	TERT	SIGNOR-279611
AKT	phosphorylation → up-regulates	TERT	SIGNOR-244361
ABL1	phosphorylation → down-regulates activity	TERT	SIGNOR-279354
AKT1	phosphorylation → up-regulates	TERT	SIGNOR-67313
SRC	phosphorylation down-regulates	TERT	SIGNOR-102097
CDK1	phosphorylation → up-regulates activity	TERT	SIGNOR-277517