Entity Details

Name AKT1_Ser280
ID O14757
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKTCHEK1Ser280AKRPRVTsGGVSESPphosphorylation
down-regulates		15107605SIGNOR-244206
AKT1CHEK1Ser280AKRPRVTsGGVSESPphosphorylation
down-regulates		15107605SIGNOR-124365
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKTphosphorylation
up-regulates
→
CHEK1
PSer280		phosphorylation
down-regulates
⊣		CHEK115107605SIGNOR-244206
AKT1phosphorylation
up-regulates
→
CHEK1
PSer280		phosphorylation
down-regulates
⊣		CHEK115107605SIGNOR-124365
Regulator Mechanism/Effect Target SIGNOR-ID
AKTphosphorylation
img/direct_inhibition.png
down-regulates 		CHEK1SIGNOR-244206
AKT1phosphorylation
img/direct_inhibition.png
down-regulates 		CHEK1SIGNOR-124365