Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
NEK2	NDC80	Ser165	LGYPFALsKSSMYTV	phosphorylation up-regulates	12386167	SIGNOR-94322
AURKB	NDC80	Ser15	SGGAGRLsMQELRSQ	phosphorylation down-regulates	20471944	SIGNOR-165554
AURKB	NDC80	Ser44	KPTFGKLsINKPTSE	phosphorylation down-regulates	20471944	SIGNOR-165558
AURKB	NDC80	Ser5 View in OncoXplorer	sVSSGGAG	phosphorylation down-regulates	20471944	SIGNOR-165562

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
NEK2	phosphorylation up-regulates →	NDC80 PSer165	phosphorylation up-regulates →	NDC80	12386167	SIGNOR-94322
AURKB	phosphorylation up-regulates →	NDC80 PSer15	phosphorylation down-regulates ⊣	NDC80	20471944	SIGNOR-165554
AURKB	phosphorylation up-regulates →	NDC80 PSer44	phosphorylation down-regulates ⊣	NDC80	20471944	SIGNOR-165558
AURKB	phosphorylation up-regulates →	NDC80 PSer5	phosphorylation down-regulates ⊣	NDC80	20471944	SIGNOR-165562

Regulator	Mechanism/Effect	Target	SIGNOR-ID
NEK2	phosphorylation → up-regulates	NDC80	SIGNOR-94322
AURKB	phosphorylation down-regulates	NDC80	SIGNOR-165554
AURKB	phosphorylation down-regulates	NDC80	SIGNOR-165558
AURKB	phosphorylation down-regulates	NDC80	SIGNOR-165562