| Name | HGS |
| ID | O14964 |
| Role | substrate |
| Enzymatic Domains |
VHS 15-143 PROSITE-ProRule
UIM 258-277 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | HGS | Tyr334 | ARYLNRNyWEKKQEE | phosphorylation up-regulates activity | 12953068 | SIGNOR-100246 |
| EGFR | HGS | Tyr329 | IDPELARyLNRNYWE | phosphorylation up-regulates | 12953068 | SIGNOR-86689 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | phosphorylation up-regulates → | HGS PTyr334 | phosphorylation up-regulates → | HGS | 12953068 | SIGNOR-100246 |
| EGFR | phosphorylation up-regulates → | HGS PTyr329 | phosphorylation up-regulates → | HGS | 12953068 | SIGNOR-86689 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EGFR | phosphorylation → up-regulates activity | HGS | SIGNOR-100246 |
| EGFR | phosphorylation → up-regulates | HGS | SIGNOR-86689 |