| Name | GAK |
| ID | O14976 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 40-314 PROSITE-ProRule
Phosphatase tensin-type 399-566 PROSITE-ProRule
C2 tensin-type 572-710 PROSITE-ProRule
J 1247-1311 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | GAK | Tyr412 | KGDLDISyITSRIAV | phosphorylation up-regulates activity | 28135906 | SIGNOR-263197 |
| SRC | GAK | Tyr1149 | CTQPRPNyASNFSVI | phosphorylation up-regulates activity | 28135906 | SIGNOR-263198 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | GAK PTyr412 | phosphorylation up-regulates → | GAK | 28135906 | SIGNOR-263197 |
| SRC | phosphorylation up-regulates → | GAK PTyr1149 | phosphorylation up-regulates → | GAK | 28135906 | SIGNOR-263198 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates activity | GAK | SIGNOR-263197 |
| SRC | phosphorylation → up-regulates activity | GAK | SIGNOR-263198 |