| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SYK | PIP5K1B | Tyr105 | FGIKPDDyLYSICSE | phosphorylation down-regulates activity | 19553680 | SIGNOR-276227 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SYK | phosphorylation up-regulates → | PIP5K1B PTyr105 | phosphorylation down-regulates ⊣ | PIP5K1B | 19553680 | SIGNOR-276227 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SYK | phosphorylation → down-regulates activity | PIP5K1B | SIGNOR-276227 |
