| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | SYN3 | Ser470 | PQGQQPLsPQSGSPQ | phosphorylation up-regulates | 14732590 | SIGNOR-121402 |
| PKA | SYN3 | – | phosphorylation down-regulates activity | 10571231 | SIGNOR-264110 | |
| CDK1 | SYN3 | Ser470 | PQGQQPLsPQSGSPQ | phosphorylation up-regulates | 14732590 | SIGNOR-121398 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | SYN3 PSer470 | phosphorylation up-regulates → | SYN3 | 14732590 | SIGNOR-121402 |
| CDK1 | phosphorylation up-regulates → | SYN3 PSer470 | phosphorylation up-regulates → | SYN3 | 14732590 | SIGNOR-121398 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation → up-regulates | SYN3 | SIGNOR-121402 |
| PKA | phosphorylation → down-regulates activity | SYN3 | SIGNOR-264110 |
| CDK1 | phosphorylation → up-regulates | SYN3 | SIGNOR-121398 |
