| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT2 | CHUK | Thr23 | EMRERLGtGGFGNVC | phosphorylation up-regulates | 19609947 | SIGNOR-187010 |
| AKT3 | CHUK | Thr23 | EMRERLGtGGFGNVC | phosphorylation up-regulates | 19609947 | SIGNOR-187062 |
| SGK1 | CHUK | Thr23 | EMRERLGtGGFGNVC | phosphorylation up-regulates activity | 19088076 | SIGNOR-278987 |
| AKT1 | CHUK | Thr23 | EMRERLGtGGFGNVC | phosphorylation up-regulates | 19609947 | SIGNOR-187006 |
| AKT | CHUK | Thr23 | EMRERLGtGGFGNVC | phosphorylation up-regulates | 19609947 | SIGNOR-244210 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT2 | phosphorylation up-regulates → | CHUK PThr23 | phosphorylation up-regulates → | CHUK | 19609947 | SIGNOR-187010 |
| AKT3 | phosphorylation up-regulates → | CHUK PThr23 | phosphorylation up-regulates → | CHUK | 19609947 | SIGNOR-187062 |
| SGK1 | phosphorylation up-regulates → | CHUK PThr23 | phosphorylation up-regulates → | CHUK | 19088076 | SIGNOR-278987 |
| AKT1 | phosphorylation up-regulates → | CHUK PThr23 | phosphorylation up-regulates → | CHUK | 19609947 | SIGNOR-187006 |
| AKT | phosphorylation up-regulates → | CHUK PThr23 | phosphorylation up-regulates → | CHUK | 19609947 | SIGNOR-244210 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT2 | phosphorylation → up-regulates | CHUK | SIGNOR-187010 |
| AKT3 | phosphorylation → up-regulates | CHUK | SIGNOR-187062 |
| SGK1 | phosphorylation → up-regulates activity | CHUK | SIGNOR-278987 |
| AKT1 | phosphorylation → up-regulates | CHUK | SIGNOR-187006 |
| AKT | phosphorylation → up-regulates | CHUK | SIGNOR-244210 |
