Entity Details

Name PPP1CA_Ser75
ID O15169
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSNK1A1AXIN1Ser75LGYEPEGsASPTPPYphosphorylation
up-regulates activity		17318175SIGNOR-249189
PPP1CAAXIN1Ser75LGYEPEGsASPTPPYdephosphorylation
down-regulates activity		17318175SIGNOR-248551
PPP1CBAXIN1Ser75LGYEPEGsASPTPPYdephosphorylation
down-regulates activity		17318175SIGNOR-248567
PPP1CCAXIN1Ser75LGYEPEGsASPTPPYdephosphorylation
down-regulates activity		17318175SIGNOR-248494
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSNK1A1phosphorylation
up-regulates
→
AXIN1
PSer75		phosphorylation
up-regulates
→		AXIN117318175SIGNOR-249189
PPP1CAdephosphorylation
down-regulates
⊣
AXIN1
PSer75		dephosphorylation
up-regulates
→		AXIN117318175SIGNOR-248551
PPP1CBdephosphorylation
down-regulates
⊣
AXIN1
PSer75		dephosphorylation
up-regulates
→		AXIN117318175SIGNOR-248567
PPP1CCdephosphorylation
down-regulates
⊣
AXIN1
PSer75		dephosphorylation
up-regulates
→		AXIN117318175SIGNOR-248494
Regulator Mechanism/Effect Target SIGNOR-ID
CSNK1A1phosphorylation
→
up-regulates activity 		AXIN1SIGNOR-249189
PPP1CAdephosphorylation
→
down-regulates activity 		AXIN1SIGNOR-248551
PPP1CBdephosphorylation
→
down-regulates activity 		AXIN1SIGNOR-248567
PPP1CCdephosphorylation
→
down-regulates activity 		AXIN1SIGNOR-248494