Entity Details

Name PPP1CC_Ser77
ID O15169
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSNK1A1AXIN1Ser77YEPEGSAsPTPPYLKphosphorylation
up-regulates activity		17318175SIGNOR-249191
PPP1CAAXIN1Ser77YEPEGSAsPTPPYLKdephosphorylation
down-regulates activity		17318175SIGNOR-248552
PPP1CCAXIN1Ser77YEPEGSAsPTPPYLKdephosphorylation
down-regulates activity		17318175SIGNOR-248495
PPP1CBAXIN1Ser77YEPEGSAsPTPPYLKdephosphorylation
down-regulates activity		17318175SIGNOR-248568
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSNK1A1phosphorylation
up-regulates
→
AXIN1
PSer77		phosphorylation
up-regulates
→		AXIN117318175SIGNOR-249191
PPP1CAdephosphorylation
down-regulates
⊣
AXIN1
PSer77		dephosphorylation
up-regulates
→		AXIN117318175SIGNOR-248552
PPP1CCdephosphorylation
down-regulates
⊣
AXIN1
PSer77		dephosphorylation
up-regulates
→		AXIN117318175SIGNOR-248495
PPP1CBdephosphorylation
down-regulates
⊣
AXIN1
PSer77		dephosphorylation
up-regulates
→		AXIN117318175SIGNOR-248568
Regulator Mechanism/Effect Target SIGNOR-ID
CSNK1A1phosphorylation
→
up-regulates activity 		AXIN1SIGNOR-249191
PPP1CAdephosphorylation
→
down-regulates activity 		AXIN1SIGNOR-248552
PPP1CCdephosphorylation
→
down-regulates activity 		AXIN1SIGNOR-248495
PPP1CBdephosphorylation
→
down-regulates activity 		AXIN1SIGNOR-248568