Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CSNK2A1	NPHP1	Ser121	PTEEEEEsESEDSED	phosphorylation up-regulates	16308564	SIGNOR-142343
PTK2B	NPHP1	Tyr349	GNQFRANyFLQPELM	phosphorylation up-regulates activity	21357692	SIGNOR-278271
PTK2B	NPHP1	Tyr721	FDLSEQTyDFLGEMR	phosphorylation up-regulates activity	21357692	SIGNOR-278273
CSNK2A1	NPHP1	Ser123	EEEEESEsEDSEDSG	phosphorylation up-regulates	16308564	SIGNOR-142347
SRC	NPHP1	Tyr721	FDLSEQTyDFLGEMR	phosphorylation up-regulates activity	21357692	SIGNOR-279122
CSNK2A1	NPHP1	Ser126	EESESEDsEDSGGEE	phosphorylation up-regulates	16308564	SIGNOR-142351
PTK2B	NPHP1	Tyr46	PNKRQHIyQRCIQLK	phosphorylation up-regulates activity	21357692	SIGNOR-278272

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CSNK2A1	phosphorylation up-regulates →	NPHP1 PSer121	phosphorylation up-regulates →	NPHP1	16308564	SIGNOR-142343
PTK2B	phosphorylation up-regulates →	NPHP1 PTyr349	phosphorylation up-regulates →	NPHP1	21357692	SIGNOR-278271
PTK2B	phosphorylation up-regulates →	NPHP1 PTyr721	phosphorylation up-regulates →	NPHP1	21357692	SIGNOR-278273
CSNK2A1	phosphorylation up-regulates →	NPHP1 PSer123	phosphorylation up-regulates →	NPHP1	16308564	SIGNOR-142347
SRC	phosphorylation up-regulates →	NPHP1 PTyr721	phosphorylation up-regulates →	NPHP1	21357692	SIGNOR-279122
CSNK2A1	phosphorylation up-regulates →	NPHP1 PSer126	phosphorylation up-regulates →	NPHP1	16308564	SIGNOR-142351
PTK2B	phosphorylation up-regulates →	NPHP1 PTyr46	phosphorylation up-regulates →	NPHP1	21357692	SIGNOR-278272

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CSNK2A1	phosphorylation → up-regulates	NPHP1	SIGNOR-142343
PTK2B	phosphorylation → up-regulates activity	NPHP1	SIGNOR-278271
PTK2B	phosphorylation → up-regulates activity	NPHP1	SIGNOR-278273
CSNK2A1	phosphorylation → up-regulates	NPHP1	SIGNOR-142347
SRC	phosphorylation → up-regulates activity	NPHP1	SIGNOR-279122
CSNK2A1	phosphorylation → up-regulates	NPHP1	SIGNOR-142351
PTK2B	phosphorylation → up-regulates activity	NPHP1	SIGNOR-278272