Entity Details

Name PPM1G
ID O15355
Role phosphatase
Enzymatic Domains
PPM-type phosphatase 26-505
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PPM1GCDKN1BThr198PGLRRRQtdephosphorylation
up-regulates activity		27822412SIGNOR-277112
PPM1GSNRPN–dephosphorylation
up-regulates quantity by stabilization		17984321SIGNOR-277021
PPM1GSRSF3–dephosphorylation
down-regulates activity		34290239SIGNOR-277048
PPM1GATM–dephosphorylation
down-regulates activity		22361354SIGNOR-277158
PPM1GUSP7–dephosphorylation
down-regulates activity		22361354SIGNOR-277159
PPM1GUSP7Ser18KAGEQQLsEPEDMEMdephosphorylation
down-regulates quantity by destabilization		22361354SIGNOR-276531
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PPM1Gdephosphorylation
down-regulates
⊣
CDKN1B
PThr198		dephosphorylation
down-regulates
⊣		CDKN1B27822412SIGNOR-277112
PPM1Gdephosphorylation
down-regulates
⊣
USP7
PSer18		dephosphorylation
up-regulates
→		USP722361354SIGNOR-276531
Regulator Mechanism/Effect Target SIGNOR-ID
PPM1Gdephosphorylation
→
up-regulates activity 		CDKN1BSIGNOR-277112
PPM1Gdephosphorylation
→
up-regulates quantity by stabilization 		SNRPNSIGNOR-277021
PPM1Gdephosphorylation
→
down-regulates activity 		SRSF3SIGNOR-277048
PPM1Gdephosphorylation
→
down-regulates activity 		ATMSIGNOR-277158
PPM1Gdephosphorylation
→
down-regulates activity 		USP7SIGNOR-277159
PPM1Gdephosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		USP7SIGNOR-276531