| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK2 | HDAC3 | Ser374 | KMLNHAPsVQIHDVP | phosphorylation down-regulates activity | 34244427 | SIGNOR-277568 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK2 | phosphorylation up-regulates → | HDAC3 PSer374 | phosphorylation down-regulates ⊣ | HDAC3 | 34244427 | SIGNOR-277568 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| HIPK2 | phosphorylation → down-regulates activity | HDAC3 | SIGNOR-277568 |
