Entity Details

Name PINK1_Ser424
ID O15379
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CSNK2A1HDAC3Ser424DHDNDKEsDVEIphosphorylation
up-regulates activity		15805470SIGNOR-250889
PINK1HDAC3Ser424DHDNDKEsDVEIphosphorylation
up-regulates activity		25305081SIGNOR-279093
PPP4CHDAC3Ser424DHDNDKEsDVEIdephosphorylation
down-regulates activity		15805470SIGNOR-248548
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CSNK2A1phosphorylation
up-regulates
→
HDAC3
PSer424		phosphorylation
up-regulates
→		HDAC315805470SIGNOR-250889
PINK1phosphorylation
up-regulates
→
HDAC3
PSer424		phosphorylation
up-regulates
→		HDAC325305081SIGNOR-279093
PPP4Cdephosphorylation
down-regulates
⊣
HDAC3
PSer424		dephosphorylation
up-regulates
→		HDAC315805470SIGNOR-248548
Regulator Mechanism/Effect Target SIGNOR-ID
CSNK2A1phosphorylation
→
up-regulates activity 		HDAC3SIGNOR-250889
PINK1phosphorylation
→
up-regulates activity 		HDAC3SIGNOR-279093
PPP4Cdephosphorylation
→
down-regulates activity 		HDAC3SIGNOR-248548