| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | RGS16 | Tyr177 | RFLKSPAyRDLAAQA | phosphorylation up-regulates | 12588871 | SIGNOR-98275 |
| EGFR | RGS16 | Tyr177 | RFLKSPAyRDLAAQA | phosphorylation up-regulates | 11602604 | SIGNOR-111024 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | RGS16 PTyr177 | phosphorylation up-regulates → | RGS16 | 12588871 | SIGNOR-98275 |
| EGFR | phosphorylation up-regulates → | RGS16 PTyr177 | phosphorylation up-regulates → | RGS16 | 11602604 | SIGNOR-111024 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates | RGS16 | SIGNOR-98275 |
| EGFR | phosphorylation → up-regulates | RGS16 | SIGNOR-111024 |
