Entity Details

Name DAPK3
ID O43293
Role kinase
Enzymatic Domains
Protein kinase 13-275
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
DAPK3MYL12BSer20KRPQRATsNVFAMFDphosphorylation
up-regulates
1178183SIGNOR-16043
DAPK3MYL12BThr19KKRPQRAtSNVFAMFphosphorylation
up-regulates
1178183SIGNOR-16047
DAPK3MYL12BThr19KKRPQRAtSNVFAMFphosphorylation
up-regulates
12429016SIGNOR-95524
DAPK3PPP1R12Aphosphorylation
down-regulates activity
20130087SIGNOR-279030
DAPK3DAPK3Ser311EYTIKSHsSLPPNNSphosphorylation
up-regulates
15611134SIGNOR-132455
DAPK3DAPK3Thr180EFKNIFGtPEFVAPEphosphorylation
up-regulates
15611134SIGNOR-132459
DAPK3DAPK3Thr225LGETKQEtLTNISAVphosphorylation
up-regulates
15611134SIGNOR-132463
DAPK3DAPK3Thr265KDPKRRMtIAQSLEHphosphorylation
up-regulates
15611134SIGNOR-132467
DAPK3DAPK3Thr299PERRRLKtTRLKEYTphosphorylation
up-regulates
15611134SIGNOR-132471
DAPK3DAPK3Thr306TTRLKEYtIKSHSSLphosphorylation
up-regulates
15611134SIGNOR-132475
DAPK3TP53Ser20PLSQETFsDLWKLLPphosphorylation
up-regulates
17339337SIGNOR-153495
DAPK3MYL9Ser20KRPQRATsNVFAMFDphosphorylation
up-regulates
19851336SIGNOR-188789
DAPK3MYL9Thr19KKRPQRAtSNVFAMFphosphorylation
up-regulates
19851336SIGNOR-188793
DAPK3CDKN1AThr145QGRKRRQtSMTDFYHphosphorylation
up-regulates quantity by stabilization
15001356SIGNOR-251085
DAPK3RPL13ASer77PYHFRAPsRIFWRTVphosphorylation
up-regulates
18995835SIGNOR-182117
DAPK3STAT3Ser727NTIDLPMsPRTLDSLphosphorylation
up-regulates activity
16219639SIGNOR-279702
DAPK3MDM2Ser166SSRRRAIsETEENSDphosphorylation
up-regulates quantity by stabilization
15001356SIGNOR-123159
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
DAPK3phosphorylation
up-regulates
MYL12B
PSer20
phosphorylation
up-regulates
MYL12B1178183SIGNOR-16043
DAPK3phosphorylation
up-regulates
MYL12B
PThr19
phosphorylation
up-regulates
MYL12B1178183SIGNOR-16047
DAPK3phosphorylation
up-regulates
MYL12B
PThr19
phosphorylation
up-regulates
MYL12B12429016SIGNOR-95524
DAPK3phosphorylation
up-regulates
DAPK3
PSer311
phosphorylation
up-regulates
DAPK315611134SIGNOR-132455
DAPK3phosphorylation
up-regulates
DAPK3
PThr180
phosphorylation
up-regulates
DAPK315611134SIGNOR-132459
DAPK3phosphorylation
up-regulates
DAPK3
PThr225
phosphorylation
up-regulates
DAPK315611134SIGNOR-132463
DAPK3phosphorylation
up-regulates
DAPK3
PThr265
phosphorylation
up-regulates
DAPK315611134SIGNOR-132467
DAPK3phosphorylation
up-regulates
DAPK3
PThr299
phosphorylation
up-regulates
DAPK315611134SIGNOR-132471
DAPK3phosphorylation
up-regulates
DAPK3
PThr306
phosphorylation
up-regulates
DAPK315611134SIGNOR-132475
DAPK3phosphorylation
up-regulates
TP53
PSer20
phosphorylation
up-regulates
TP5317339337SIGNOR-153495
DAPK3phosphorylation
up-regulates
MYL9
PSer20
phosphorylation
up-regulates
MYL919851336SIGNOR-188789
DAPK3phosphorylation
up-regulates
MYL9
PThr19
phosphorylation
up-regulates
MYL919851336SIGNOR-188793
DAPK3phosphorylation
up-regulates
CDKN1A
PThr145
phosphorylation
up-regulates
CDKN1A15001356SIGNOR-251085
DAPK3phosphorylation
up-regulates
RPL13A
PSer77
phosphorylation
up-regulates
RPL13A18995835SIGNOR-182117
DAPK3phosphorylation
up-regulates
STAT3
PSer727
phosphorylation
up-regulates
STAT316219639SIGNOR-279702
DAPK3phosphorylation
up-regulates
MDM2
PSer166
phosphorylation
up-regulates
MDM215001356SIGNOR-123159
Regulator Mechanism/Effect Target SIGNOR-ID
DAPK3phosphorylation

up-regulates
MYL12BSIGNOR-16043
DAPK3phosphorylation

up-regulates
MYL12BSIGNOR-16047
DAPK3phosphorylation

up-regulates
MYL12BSIGNOR-95524
DAPK3phosphorylation

down-regulates activity
PPP1R12ASIGNOR-279030
DAPK3phosphorylation

up-regulates
DAPK3SIGNOR-132455
DAPK3phosphorylation

up-regulates
DAPK3SIGNOR-132459
DAPK3phosphorylation

up-regulates
DAPK3SIGNOR-132463
DAPK3phosphorylation

up-regulates
DAPK3SIGNOR-132467
DAPK3phosphorylation

up-regulates
DAPK3SIGNOR-132471
DAPK3phosphorylation

up-regulates
DAPK3SIGNOR-132475
DAPK3phosphorylation

up-regulates
TP53SIGNOR-153495
DAPK3phosphorylation

up-regulates
MYL9SIGNOR-188789
DAPK3phosphorylation

up-regulates
MYL9SIGNOR-188793
DAPK3phosphorylation

up-regulates quantity by stabilization
CDKN1ASIGNOR-251085
DAPK3phosphorylation

up-regulates
RPL13ASIGNOR-182117
DAPK3phosphorylation

up-regulates activity
STAT3SIGNOR-279702
DAPK3phosphorylation

up-regulates quantity by stabilization
MDM2SIGNOR-123159