| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FYN | TGFB1I1 | Tyr60 | SGDKDHLySTVCKPR | phosphorylation up-regulates activity | 10838081 | SIGNOR-262875 |
| PTK2B | TGFB1I1 | Tyr60 | SGDKDHLySTVCKPR | phosphorylation up-regulates activity | 10838081 | SIGNOR-262876 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FYN | phosphorylation up-regulates → | TGFB1I1 PTyr60 | phosphorylation up-regulates → | TGFB1I1 | 10838081 | SIGNOR-262875 |
| PTK2B | phosphorylation up-regulates → | TGFB1I1 PTyr60 | phosphorylation up-regulates → | TGFB1I1 | 10838081 | SIGNOR-262876 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| FYN | phosphorylation → up-regulates activity | TGFB1I1 | SIGNOR-262875 |
| PTK2B | phosphorylation → up-regulates activity | TGFB1I1 | SIGNOR-262876 |