Entity Details

Name RIPK2
ID O43353
Role substrate
Enzymatic Domains
Protein kinase 18-294
PROSITE-ProRule
CARD 432-524
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
LRRK2RIPK2Ser176
View in OncoXplorer
KWRMMSLsQSRSSKSphosphorylation
up-regulates activity		27830463SIGNOR-278953
RIPK2RIPK2Ser176
View in OncoXplorer
KWRMMSLsQSRSSKSphosphorylation
up-regulates activity		16824733SIGNOR-229701
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
LRRK2phosphorylation
up-regulates
→
RIPK2
PSer176		phosphorylation
up-regulates
→		RIPK227830463SIGNOR-278953
RIPK2phosphorylation
up-regulates
→
RIPK2
PSer176		phosphorylation
up-regulates
→		RIPK216824733SIGNOR-229701
Regulator Mechanism/Effect Target SIGNOR-ID
LRRK2phosphorylation
→
up-regulates activity 		RIPK2SIGNOR-278953
RIPK2phosphorylation
→
up-regulates activity 		RIPK2SIGNOR-229701