| Name | FRS3 |
| ID | O43559 |
| Role | substrate |
| Enzymatic Domains |
IRS-type PTB 13-115 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NTRK2 | FRS3 | Tyr455 | PARSSDSyAVIDLKK | phosphorylation up-regulates activity | 11432792 | SIGNOR-250203 |
| NTRK2 | FRS3 | Tyr417 | EPPRQLNyIQVELKG | phosphorylation up-regulates activity | 11432792 | SIGNOR-250202 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| NTRK2 | phosphorylation up-regulates → | FRS3 PTyr455 | phosphorylation up-regulates → | FRS3 | 11432792 | SIGNOR-250203 |
| NTRK2 | phosphorylation up-regulates → | FRS3 PTyr417 | phosphorylation up-regulates → | FRS3 | 11432792 | SIGNOR-250202 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| NTRK2 | phosphorylation → up-regulates activity | FRS3 | SIGNOR-250203 |
| NTRK2 | phosphorylation → up-regulates activity | FRS3 | SIGNOR-250202 |