| Name | RGS14 |
| ID | O43566 |
| Role | substrate |
| Enzymatic Domains |
RGS 67-184 PROSITE-ProRule
RBD 1 302-373 PROSITE-ProRule
RBD 2 375-445 PROSITE-ProRule
GoLoco 498-521 PROSITE-ProRule |
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|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | RGS14 | Ser260 | NAALRREsQGSLNSS | phosphorylation up-regulates activity | 12534294 | SIGNOR-250045 |
| PRKACA | RGS14 | Thr495 | SATGKRQtCDIEGLV | phosphorylation up-regulates activity | 12534294 | SIGNOR-250046 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKACA | phosphorylation up-regulates → | RGS14 PSer260 | phosphorylation up-regulates → | RGS14 | 12534294 | SIGNOR-250045 |
| PRKACA | phosphorylation up-regulates → | RGS14 PThr495 | phosphorylation up-regulates → | RGS14 | 12534294 | SIGNOR-250046 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKACA | phosphorylation → up-regulates activity | RGS14 | SIGNOR-250045 |
| PRKACA | phosphorylation → up-regulates activity | RGS14 | SIGNOR-250046 |