| Name | PSTPIP1 |
| ID | O43586 |
| Role | substrate |
| Enzymatic Domains |
F-BAR 5-264 PROSITE-ProRule
SH3 359-416 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | PSTPIP1 | Tyr345 | PERNEGVyTAIAVQE | phosphorylation unknown | 11163214 | SIGNOR-260809 |
| ABL1 | PSTPIP1 | Tyr345 | PERNEGVyTAIAVQE | phosphorylation up-regulates activity | 11163214 | SIGNOR-251431 |
| ABL1 | PSTPIP1 | Tyr345 | PERNEGVyTAIAVQE | phosphorylation unknown | 11163214 | SIGNOR-246219 |
| PTPN12 | PSTPIP1 | Tyr345 | PERNEGVyTAIAVQE | dephosphorylation down-regulates activity | 11711533 | SIGNOR-248656 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | phosphorylation up-regulates → | PSTPIP1 PTyr345 | phosphorylation down-regulates ⊣ | PSTPIP1 | 11163214 | SIGNOR-260809 |
| ABL1 | phosphorylation up-regulates → | PSTPIP1 PTyr345 | phosphorylation up-regulates → | PSTPIP1 | 11163214 | SIGNOR-251431 |
| ABL1 | phosphorylation up-regulates → | PSTPIP1 PTyr345 | phosphorylation down-regulates ⊣ | PSTPIP1 | 11163214 | SIGNOR-246219 |
| PTPN12 | dephosphorylation down-regulates ⊣ | PSTPIP1 PTyr345 | dephosphorylation up-regulates → | PSTPIP1 | 11711533 | SIGNOR-248656 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ABL1 | phosphorylation → unknown | PSTPIP1 | SIGNOR-260809 |
| ABL1 | phosphorylation → up-regulates activity | PSTPIP1 | SIGNOR-251431 |
| ABL1 | phosphorylation → unknown | PSTPIP1 | SIGNOR-246219 |
| PTPN12 | dephosphorylation → down-regulates activity | PSTPIP1 | SIGNOR-248656 |