| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LIMK2 | SPOP | Ser59 | IKSSTFSsGANDKLK | phosphorylation down-regulates activity | 33311589 | SIGNOR-278337 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LIMK2 | phosphorylation up-regulates → | SPOP PSer59 | phosphorylation down-regulates ⊣ | SPOP | 33311589 | SIGNOR-278337 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LIMK2 | phosphorylation → down-regulates activity | SPOP | SIGNOR-278337 |