| Name | KALRN |
| ID | O60229 |
| Role | substrate |
| Enzymatic Domains |
CRAL-TRIO 35-180 PROSITE-ProRule
DH 1 1281-1456 PROSITE-ProRule
PH 1 1468-1580 PROSITE-ProRule
SH3 1 1646-1711 PROSITE-ProRule
DH 2 1929-2104 PROSITE-ProRule
PH 2 2116-2226 PROSITE-ProRule
SH3 2 2321-2386 PROSITE-ProRule
Ig-like C2-type 2471-2564
Fibronectin type-III 2571-2665 PROSITE-ProRule
Protein kinase 2684-2938 PROSITE-ProRule |
View in  |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPKAPK5 | KALRN | Ser487 | DVLQRPLsPGNSESL | phosphorylation up-regulates activity | 22508986 | SIGNOR-263093 |
| CDK5 | KALRN | – | phosphorylation up-regulates activity | 18628310 | SIGNOR-279603 | |
| MAPK6 | KALRN | – | phosphorylation up-regulates activity | 22508986 | SIGNOR-263094 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPKAPK5 | phosphorylation up-regulates → | KALRN PSer487 | phosphorylation up-regulates → | KALRN | 22508986 | SIGNOR-263093 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPKAPK5 | phosphorylation → up-regulates activity | KALRN | SIGNOR-263093 |
| CDK5 | phosphorylation → up-regulates activity | KALRN | SIGNOR-279603 |
| MAPK6 | phosphorylation → up-regulates activity | KALRN | SIGNOR-263094 |