| Name | HBP1 |
| ID | O60381 |
| Role | substrate |
| Enzymatic Domains |
AXH 203-345 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PIM1 | HBP1 | Ser372 | SAVYVLSsMARQRRA | phosphorylation up-regulates activity | 28348080 | SIGNOR-277346 |
| MAPK11 | HBP1 | Ser402 | GFSKNCGsPGSSQLS | phosphorylation up-regulates | 14612426 | SIGNOR-119134 |
| MAPK14 | HBP1 | Ser402 | GFSKNCGsPGSSQLS | phosphorylation up-regulates | 14612426 | SIGNOR-119138 |
| PIM1 | HBP1 | Ser380 | MARQRRAsLSCGGPG | phosphorylation up-regulates activity | 28348080 | SIGNOR-277347 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PIM1 | phosphorylation up-regulates → | HBP1 PSer372 | phosphorylation up-regulates → | HBP1 | 28348080 | SIGNOR-277346 |
| MAPK11 | phosphorylation up-regulates → | HBP1 PSer402 | phosphorylation up-regulates → | HBP1 | 14612426 | SIGNOR-119134 |
| MAPK14 | phosphorylation up-regulates → | HBP1 PSer402 | phosphorylation up-regulates → | HBP1 | 14612426 | SIGNOR-119138 |
| PIM1 | phosphorylation up-regulates → | HBP1 PSer380 | phosphorylation up-regulates → | HBP1 | 28348080 | SIGNOR-277347 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PIM1 | phosphorylation → up-regulates activity | HBP1 | SIGNOR-277346 |
| MAPK11 | phosphorylation → up-regulates | HBP1 | SIGNOR-119134 |
| MAPK14 | phosphorylation → up-regulates | HBP1 | SIGNOR-119138 |
| PIM1 | phosphorylation → up-regulates activity | HBP1 | SIGNOR-277347 |