Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK1	BUB1B	Thr620	RAARFVStPFHEIMS	phosphorylation up-regulates	17785528	SIGNOR-157642
PLK1	BUB1B	Thr680	IEDSREAtHSSGFSG	phosphorylation up-regulates	23079597	SIGNOR-199222
CHEK1	BUB1B	–		phosphorylation up-regulates activity	19778378	SIGNOR-280223
PLK1	BUB1B	Ser676	LSPIIEDsREATHSS	phosphorylation up-regulates	17785528	SIGNOR-157646
PLK1	BUB1B	Thr1008	LNANDEAtVSVLGEL	phosphorylation up-regulates	17376779	SIGNOR-153863
PLK1	BUB1B	Thr792	PRNSAELtVIKVSSQ	phosphorylation up-regulates	17376779	SIGNOR-153867

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK1	phosphorylation up-regulates →	BUB1B PThr620	phosphorylation up-regulates →	BUB1B	17785528	SIGNOR-157642
PLK1	phosphorylation up-regulates →	BUB1B PThr680	phosphorylation up-regulates →	BUB1B	23079597	SIGNOR-199222
PLK1	phosphorylation up-regulates →	BUB1B PSer676	phosphorylation up-regulates →	BUB1B	17785528	SIGNOR-157646
PLK1	phosphorylation up-regulates →	BUB1B PThr1008	phosphorylation up-regulates →	BUB1B	17376779	SIGNOR-153863
PLK1	phosphorylation up-regulates →	BUB1B PThr792	phosphorylation up-regulates →	BUB1B	17376779	SIGNOR-153867

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK1	phosphorylation → up-regulates	BUB1B	SIGNOR-157642
PLK1	phosphorylation → up-regulates	BUB1B	SIGNOR-199222
CHEK1	phosphorylation → up-regulates activity	BUB1B	SIGNOR-280223
PLK1	phosphorylation → up-regulates	BUB1B	SIGNOR-157646
PLK1	phosphorylation → up-regulates	BUB1B	SIGNOR-153863
PLK1	phosphorylation → up-regulates	BUB1B	SIGNOR-153867