Entity Details

Name PDE8A
ID O60658
Role substrate
Enzymatic Domains
PAS 213-283
PROSITE-ProRule
PAC 287-329
PDEase 480-820
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PKAPDE8ASer359
View in OncoXplorer
HKDRRKGsLDVKAVAphosphorylation
up-regulates activity		22673573SIGNOR-273783
PKAPDE8ASer359
View in OncoXplorer
HKDRRKGsLDVKAVAphosphorylation
up-regulates activity		22673573SIGNOR-276416
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PKAphosphorylation
up-regulates
→
PDE8A
PSer359		phosphorylation
up-regulates
→		PDE8A22673573SIGNOR-273783
PKAphosphorylation
up-regulates
→
PDE8A
PSer359		phosphorylation
up-regulates
→		PDE8A22673573SIGNOR-276416
Regulator Mechanism/Effect Target SIGNOR-ID
PKAphosphorylation
→
up-regulates activity 		PDE8ASIGNOR-273783
PKAphosphorylation
→
up-regulates activity 		PDE8ASIGNOR-276416