Entity Details

Name BRD4
ID O60885
Role substrate
Enzymatic Domains
Bromo 1 58-164
PROSITE-ProRule
Bromo 2 348-457
PROSITE-ProRule
NET 600-682
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
JAK2BRD4Tyr98KLNLPDYyKIIKTPMphosphorylation
up-regulates quantity by stabilization		34290255SIGNOR-277312
JAK2BRD4Tyr97VKLNLPDyYKIIKTPphosphorylation
up-regulates quantity by stabilization		34290255SIGNOR-277313
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
JAK2phosphorylation
up-regulates
→
BRD4
PTyr98		phosphorylation
up-regulates
→		BRD434290255SIGNOR-277312
JAK2phosphorylation
up-regulates
→
BRD4
PTyr97		phosphorylation
up-regulates
→		BRD434290255SIGNOR-277313
Regulator Mechanism/Effect Target SIGNOR-ID
JAK2phosphorylation
→
up-regulates quantity by stabilization 		BRD4SIGNOR-277312
JAK2phosphorylation
→
up-regulates quantity by stabilization 		BRD4SIGNOR-277313