| Name | NBN |
| ID | O60934 |
| Role | substrate |
| Enzymatic Domains |
FHA 24-83 PROSITE-ProRule
BRCT 1 105-181 PubMed
BRCT 2 224-315 PubMed |
View in ![]() |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | NBN | Ser278 | VDTGITNsQTLIPDC | phosphorylation up-regulates | 10839544 | SIGNOR-78025 |
| ATM | NBN | Ser343 | TTPGPSLsQGVSVDE | phosphorylation up-regulates | 10608806 | SIGNOR-73432 |
| CDK2 | NBN | Ser432 | RIPNYQLsPTKLPSI | phosphorylation up-regulates activity | 22927831 | SIGNOR-279500 |
| ATM | NBN | Ser615 | VPESSKIsQENEIGK | phosphorylation up-regulates | 10839545 | SIGNOR-78034 |
| ATM | NBN | Ser397 | EQKFRMLsQDAPTVK | phosphorylation up-regulates | 10839545 | SIGNOR-78030 |
| ATR | NBN | Ser343 | TTPGPSLsQGVSVDE | phosphorylation up-regulates | 17526493 | SIGNOR-155214 |
| ATM | NBN | Ser343 | TTPGPSLsQGVSVDE | phosphorylation up-regulates | 10802669 | SIGNOR-77149 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATM | phosphorylation up-regulates → | NBN PSer278 | phosphorylation up-regulates → | NBN | 10839544 | SIGNOR-78025 |
| ATM | phosphorylation up-regulates → | NBN PSer343 | phosphorylation up-regulates → | NBN | 10608806 | SIGNOR-73432 |
| CDK2 | phosphorylation up-regulates → | NBN PSer432 | phosphorylation up-regulates → | NBN | 22927831 | SIGNOR-279500 |
| ATM | phosphorylation up-regulates → | NBN PSer615 | phosphorylation up-regulates → | NBN | 10839545 | SIGNOR-78034 |
| ATM | phosphorylation up-regulates → | NBN PSer397 | phosphorylation up-regulates → | NBN | 10839545 | SIGNOR-78030 |
| ATR | phosphorylation up-regulates → | NBN PSer343 | phosphorylation up-regulates → | NBN | 17526493 | SIGNOR-155214 |
| ATM | phosphorylation up-regulates → | NBN PSer343 | phosphorylation up-regulates → | NBN | 10802669 | SIGNOR-77149 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-78025 |
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-73432 |
| CDK2 | phosphorylation → up-regulates activity | NBN | SIGNOR-279500 |
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-78034 |
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-78030 |
| ATR | phosphorylation → up-regulates | NBN | SIGNOR-155214 |
| ATM | phosphorylation → up-regulates | NBN | SIGNOR-77149 |