| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | MITF | Ser516 | KTSSRRSsMSMEETE | phosphorylation down-regulates quantity by destabilization | 27702651 | SIGNOR-277281 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | MITF PSer516 | phosphorylation down-regulates ⊣ | MITF | 27702651 | SIGNOR-277281 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation down-regulates quantity by destabilization | MITF | SIGNOR-277281 |
