| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA1 | MITF | Ser409 | HGLSLIPsTGLCSPD | phosphorylation down-regulates | 10673502 | SIGNOR-75034 |
| RPS6K | MITF | Ser409 | HGLSLIPsTGLCSPD | phosphorylation down-regulates | 21749389 | SIGNOR-252795 |
| RPS6K | MITF | Ser409 | HGLSLIPsTGLCSPD | phosphorylation down-regulates | 10673502 | SIGNOR-252791 |
| RPS6KA1 | MITF | Ser409 | HGLSLIPsTGLCSPD | phosphorylation down-regulates | 21749389 | SIGNOR-174760 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA1 | phosphorylation up-regulates → | MITF PSer409 | phosphorylation down-regulates ⊣ | MITF | 10673502 | SIGNOR-75034 |
| RPS6K | phosphorylation up-regulates → | MITF PSer409 | phosphorylation down-regulates ⊣ | MITF | 21749389 | SIGNOR-252795 |
| RPS6K | phosphorylation up-regulates → | MITF PSer409 | phosphorylation down-regulates ⊣ | MITF | 10673502 | SIGNOR-252791 |
| RPS6KA1 | phosphorylation up-regulates → | MITF PSer409 | phosphorylation down-regulates ⊣ | MITF | 21749389 | SIGNOR-174760 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KA1 | phosphorylation down-regulates | MITF | SIGNOR-75034 |
| RPS6K | phosphorylation down-regulates | MITF | SIGNOR-252795 |
| RPS6K | phosphorylation down-regulates | MITF | SIGNOR-252791 |
| RPS6KA1 | phosphorylation down-regulates | MITF | SIGNOR-174760 |
