Entity Details

Name ICOSLG
ID O75144
Role substrate
Enzymatic Domains
Ig-like V-type 19-129
Ig-like C2-type 141-227
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCAICOSLGSer285RDRCLQHsYAGAWAVphosphorylation
up-regulates activity		24837102SIGNOR-273798
PRKCBICOSLGSer285RDRCLQHsYAGAWAVphosphorylation
up-regulates activity		24837102SIGNOR-273797
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCAphosphorylation
up-regulates
→
ICOSLG
PSer285		phosphorylation
up-regulates
→		ICOSLG24837102SIGNOR-273798
PRKCBphosphorylation
up-regulates
→
ICOSLG
PSer285		phosphorylation
up-regulates
→		ICOSLG24837102SIGNOR-273797
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCAphosphorylation
→
up-regulates activity 		ICOSLGSIGNOR-273798
PRKCBphosphorylation
→
up-regulates activity 		ICOSLGSIGNOR-273797