| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | ULK1 | Ser638 | FDFPKTPsSQNLLAL | phosphorylation up-regulates | 19584320 | SIGNOR-216499 |
| AMPK | ULK1 | Ser638 | FDFPKTPsSQNLLAL | phosphorylation up-regulates | 21205641 | SIGNOR-216461 |
| PRKAA2 | ULK1 | Ser638 | FDFPKTPsSQNLLAL | phosphorylation up-regulates | 19584320 | SIGNOR-186641 |
| PRKAA2 | ULK1 | Ser638 | FDFPKTPsSQNLLAL | phosphorylation up-regulates | 21205641 | SIGNOR-170867 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AMPK | phosphorylation up-regulates → | ULK1 PSer638 | phosphorylation up-regulates → | ULK1 | 19584320 | SIGNOR-216499 |
| AMPK | phosphorylation up-regulates → | ULK1 PSer638 | phosphorylation up-regulates → | ULK1 | 21205641 | SIGNOR-216461 |
| PRKAA2 | phosphorylation up-regulates → | ULK1 PSer638 | phosphorylation up-regulates → | ULK1 | 19584320 | SIGNOR-186641 |
| PRKAA2 | phosphorylation up-regulates → | ULK1 PSer638 | phosphorylation up-regulates → | ULK1 | 21205641 | SIGNOR-170867 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AMPK | phosphorylation → up-regulates | ULK1 | SIGNOR-216499 |
| AMPK | phosphorylation → up-regulates | ULK1 | SIGNOR-216461 |
| PRKAA2 | phosphorylation → up-regulates | ULK1 | SIGNOR-186641 |
| PRKAA2 | phosphorylation → up-regulates | ULK1 | SIGNOR-170867 |
