| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | ULK1 | Ser423 | GRAGPFSsSRCGASV | phosphorylation down-regulates quantity by destabilization | 35931119 | SIGNOR-277900 |
| PRKCA | ULK1 | Ser423 | GRAGPFSsSRCGASV | phosphorylation down-regulates activity | 30154410 | SIGNOR-279558 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | ULK1 PSer423 | phosphorylation down-regulates ⊣ | ULK1 | 35931119 | SIGNOR-277900 |
| PRKCA | phosphorylation up-regulates → | ULK1 PSer423 | phosphorylation down-regulates ⊣ | ULK1 | 30154410 | SIGNOR-279558 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCA | phosphorylation![]() down-regulates quantity by destabilization | ULK1 | SIGNOR-277900 |
| PRKCA | phosphorylation → down-regulates activity | ULK1 | SIGNOR-279558 |