| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PBK | ULK1 | Ser495 | GVLARKMsLGGGRPY | phosphorylation down-regulates activity | 31378785 | SIGNOR-277473 |
| STK38L | ULK1 | Ser495 | GVLARKMsLGGGRPY | phosphorylation down-regulates quantity | 35670107 | SIGNOR-270348 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PBK | phosphorylation up-regulates → | ULK1 PSer495 | phosphorylation down-regulates ⊣ | ULK1 | 31378785 | SIGNOR-277473 |
| STK38L | phosphorylation up-regulates → | ULK1 PSer495 | phosphorylation down-regulates ⊣ | ULK1 | 35670107 | SIGNOR-270348 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PBK | phosphorylation → down-regulates activity | ULK1 | SIGNOR-277473 |
| STK38L | phosphorylation → down-regulates quantity | ULK1 | SIGNOR-270348 |
