Entity Details

Name E2F6
ID O75461
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CHEK1E2F6Ser52EDNVQYVsMRKALKVphosphorylation
down-regulates activity		23954429SIGNOR-266371
CHEK1E2F6Ser12RPARKLPsLLLDPTEphosphorylation
down-regulates activity		23954429SIGNOR-266370
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CHEK1phosphorylation
up-regulates
→
E2F6
PSer52		phosphorylation
down-regulates
⊣		E2F623954429SIGNOR-266371
CHEK1phosphorylation
up-regulates
→
E2F6
PSer12		phosphorylation
down-regulates
⊣		E2F623954429SIGNOR-266370
Regulator Mechanism/Effect Target SIGNOR-ID
CHEK1phosphorylation
→
down-regulates activity 		E2F6SIGNOR-266371
CHEK1phosphorylation
→
down-regulates activity 		E2F6SIGNOR-266370