| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | SF3B1 | Thr244 | GRAKGSEtPGATPGS | phosphorylation up-regulates | 12105215 | SIGNOR-90434 |
| CyclinE/CDK2 | SF3B1 | Thr244 | GRAKGSEtPGATPGS | phosphorylation up-regulates | 12105215 | SIGNOR-216686 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | SF3B1 PThr244 | phosphorylation up-regulates → | SF3B1 | 12105215 | SIGNOR-90434 |
| CyclinE/CDK2 | phosphorylation up-regulates → | SF3B1 PThr244 | phosphorylation up-regulates → | SF3B1 | 12105215 | SIGNOR-216686 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation → up-regulates | SF3B1 | SIGNOR-90434 |
| CyclinE/CDK2 | phosphorylation → up-regulates | SF3B1 | SIGNOR-216686 |
