Entity Details

Name DAB1
ID O75553
Role substrate
Enzymatic Domains
PID 36-189
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCDAB1Tyr232SQKKEGVyDVPKSQPphosphorylation
up-regulates activity		11279201SIGNOR-247084
SRCDAB1Tyr220PETEENIyQVPTSQKphosphorylation
up-regulates activity		11279201SIGNOR-247080
SRCDAB1Tyr198EDVEDPVyQYIVFEAphosphorylation
up-regulates activity		11279201SIGNOR-247076
FYNDAB1–phosphorylation
down-regulates activity		21534960SIGNOR-278476
SRCDAB1Tyr185KQCEQAVyQTILEEDphosphorylation
up-regulates activity		11279201SIGNOR-247072
PTPRGDAB1Tyr198EDVEDPVyQYIVFEAdephosphorylation
down-regulates activity		25624455SIGNOR-254697
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
DAB1
PTyr232		phosphorylation
up-regulates
→		DAB111279201SIGNOR-247084
SRCphosphorylation
up-regulates
→
DAB1
PTyr220		phosphorylation
up-regulates
→		DAB111279201SIGNOR-247080
SRCphosphorylation
up-regulates
→
DAB1
PTyr198		phosphorylation
up-regulates
→		DAB111279201SIGNOR-247076
SRCphosphorylation
up-regulates
→
DAB1
PTyr185		phosphorylation
up-regulates
→		DAB111279201SIGNOR-247072
PTPRGdephosphorylation
down-regulates
⊣
DAB1
PTyr198		dephosphorylation
up-regulates
→		DAB125624455SIGNOR-254697
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates activity 		DAB1SIGNOR-247084
SRCphosphorylation
→
up-regulates activity 		DAB1SIGNOR-247080
SRCphosphorylation
→
up-regulates activity 		DAB1SIGNOR-247076
FYNphosphorylation
→
down-regulates activity 		DAB1SIGNOR-278476
SRCphosphorylation
→
up-regulates activity 		DAB1SIGNOR-247072
PTPRGdephosphorylation
→
down-regulates activity 		DAB1SIGNOR-254697