| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPRG | DAB1 | Tyr198 | EDVEDPVyQYIVFEA | dephosphorylation down-regulates activity | 25624455 | SIGNOR-254697 |
| SRC | DAB1 | Tyr198 | EDVEDPVyQYIVFEA | phosphorylation up-regulates activity | 11279201 | SIGNOR-247076 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPRG | dephosphorylation down-regulates ⊣ | DAB1 PTyr198 | dephosphorylation up-regulates → | DAB1 | 25624455 | SIGNOR-254697 |
| SRC | phosphorylation up-regulates → | DAB1 PTyr198 | phosphorylation up-regulates → | DAB1 | 11279201 | SIGNOR-247076 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPRG | dephosphorylation → down-regulates activity | DAB1 | SIGNOR-254697 |
| SRC | phosphorylation → up-regulates activity | DAB1 | SIGNOR-247076 |
