Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
EGFR	STAM2	Tyr192	HTETKSLyPSSEIQL	phosphorylation unknown	11687594	SIGNOR-251097
PTPN1	STAM2	Tyr291	KSEPEPVyIDEDKMD	dephosphorylation up-regulates quantity by stabilization	20504764	SIGNOR-248406

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
EGFR	phosphorylation up-regulates →	STAM2 PTyr192	phosphorylation down-regulates ⊣	STAM2	11687594	SIGNOR-251097
PTPN1	dephosphorylation down-regulates ⊣	STAM2 PTyr291	dephosphorylation down-regulates ⊣	STAM2	20504764	SIGNOR-248406

Regulator	Mechanism/Effect	Target	SIGNOR-ID
EGFR	phosphorylation → unknown	STAM2	SIGNOR-251097
PTPN1	dephosphorylation → up-regulates quantity by stabilization	STAM2	SIGNOR-248406