Entity Details

Name PIAS2
ID O75928
Role substrate
Enzymatic Domains
SAP 11-45
PROSITE-ProRule
PINIT 134-299
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK14PIAS2Ser113STSVTPHsPSSPVGSphosphorylation
up-regulates activity		16713578SIGNOR-262948
MAPK11PIAS2Ser113STSVTPHsPSSPVGSphosphorylation
up-regulates activity		16713578SIGNOR-262946
MAPK11PIAS2Ser116VTPHSPSsPVGSVLLphosphorylation
up-regulates activity		16713578SIGNOR-262947
MAPK14PIAS2Ser116VTPHSPSsPVGSVLLphosphorylation
up-regulates activity		16713578SIGNOR-262949
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK14phosphorylation
up-regulates
→
PIAS2
PSer113		phosphorylation
up-regulates
→		PIAS216713578SIGNOR-262948
MAPK11phosphorylation
up-regulates
→
PIAS2
PSer113		phosphorylation
up-regulates
→		PIAS216713578SIGNOR-262946
MAPK11phosphorylation
up-regulates
→
PIAS2
PSer116		phosphorylation
up-regulates
→		PIAS216713578SIGNOR-262947
MAPK14phosphorylation
up-regulates
→
PIAS2
PSer116		phosphorylation
up-regulates
→		PIAS216713578SIGNOR-262949
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK14phosphorylation
→
up-regulates activity 		PIAS2SIGNOR-262948
MAPK11phosphorylation
→
up-regulates activity 		PIAS2SIGNOR-262946
MAPK11phosphorylation
→
up-regulates activity 		PIAS2SIGNOR-262947
MAPK14phosphorylation
→
up-regulates activity 		PIAS2SIGNOR-262949