Entity Details

Name CDKL5
ID O76039
Role substrate
Enzymatic Domains
Protein kinase 13-297
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDKL5CDKL5Thr169EGNNANYtEYVATRWphosphorylation
up-regulates activity		16935860SIGNOR-262289
CDKL5CDKL5Tyr171
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NNANYTEyVATRWYRphosphorylation
up-regulates activity		16935860SIGNOR-245876
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDKL5phosphorylation
up-regulates
→
CDKL5
PThr169		phosphorylation
up-regulates
→		CDKL516935860SIGNOR-262289
CDKL5phosphorylation
up-regulates
→
CDKL5
PTyr171		phosphorylation
up-regulates
→		CDKL516935860SIGNOR-245876
Regulator Mechanism/Effect Target SIGNOR-ID
CDKL5phosphorylation
→
up-regulates activity 		CDKL5SIGNOR-262289
CDKL5phosphorylation
→
up-regulates activity 		CDKL5SIGNOR-245876