Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK5	TPPP	Ser18 View in OncoXplorer	ANRTPPKsPGDPSKD	phosphorylation down-regulates activity	17693641	SIGNOR-262932
CDK5	TPPP	Thr14 View in OncoXplorer	PAKAANRtPPKSPGD	phosphorylation down-regulates activity	17693641	SIGNOR-262933
MAPK1	TPPP	Ser18 View in OncoXplorer	ANRTPPKsPGDPSKD	phosphorylation down-regulates activity	17693641	SIGNOR-262929
MAPK1	TPPP	Ser160 View in OncoXplorer	GVTKAISsPTVSRLT	phosphorylation down-regulates activity	17693641	SIGNOR-262928
CDK5	TPPP	Ser160 View in OncoXplorer	GVTKAISsPTVSRLT	phosphorylation down-regulates activity	17693641	SIGNOR-262931
PRKACA	TPPP	Ser32 View in OncoXplorer	DRAAKRLsLESEGAG	phosphorylation unknown	17693641	SIGNOR-262930

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK5	phosphorylation up-regulates →	TPPP PSer18	phosphorylation down-regulates ⊣	TPPP	17693641	SIGNOR-262932
CDK5	phosphorylation up-regulates →	TPPP PThr14	phosphorylation down-regulates ⊣	TPPP	17693641	SIGNOR-262933
MAPK1	phosphorylation up-regulates →	TPPP PSer18	phosphorylation down-regulates ⊣	TPPP	17693641	SIGNOR-262929
MAPK1	phosphorylation up-regulates →	TPPP PSer160	phosphorylation down-regulates ⊣	TPPP	17693641	SIGNOR-262928
CDK5	phosphorylation up-regulates →	TPPP PSer160	phosphorylation down-regulates ⊣	TPPP	17693641	SIGNOR-262931
PRKACA	phosphorylation up-regulates →	TPPP PSer32	phosphorylation down-regulates ⊣	TPPP	17693641	SIGNOR-262930

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK5	phosphorylation → down-regulates activity	TPPP	SIGNOR-262932
CDK5	phosphorylation → down-regulates activity	TPPP	SIGNOR-262933
MAPK1	phosphorylation → down-regulates activity	TPPP	SIGNOR-262929
MAPK1	phosphorylation → down-regulates activity	TPPP	SIGNOR-262928
CDK5	phosphorylation → down-regulates activity	TPPP	SIGNOR-262931
PRKACA	phosphorylation → unknown	TPPP	SIGNOR-262930