Entity Details

Name SUN1
ID O94901
Role substrate
Enzymatic Domains
SUN 622-784
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PLK1SUN1Ser138
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RPPVLDEsWIREQTTphosphorylation
down-regulates activity		25482198SIGNOR-263098
PKCSUN1Ser113HVSRQVTsSGVSHGGphosphorylation
down-regulates activity		28831067SIGNOR-263281
CDK1SUN1Ser48
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KLDPVFDsPRMSRRSphosphorylation
down-regulates activity		25482198SIGNOR-263099
CDK1SUN1Ser334FLLLAGLsLRGQGNFphosphorylation
down-regulates activity		25482198SIGNOR-263100
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PLK1phosphorylation
up-regulates
→
SUN1
PSer138		phosphorylation
down-regulates
⊣		SUN125482198SIGNOR-263098
PKCphosphorylation
up-regulates
→
SUN1
PSer113		phosphorylation
down-regulates
⊣		SUN128831067SIGNOR-263281
CDK1phosphorylation
up-regulates
→
SUN1
PSer48		phosphorylation
down-regulates
⊣		SUN125482198SIGNOR-263099
CDK1phosphorylation
up-regulates
→
SUN1
PSer334		phosphorylation
down-regulates
⊣		SUN125482198SIGNOR-263100
Regulator Mechanism/Effect Target SIGNOR-ID
PLK1phosphorylation
→
down-regulates activity 		SUN1SIGNOR-263098
PKCphosphorylation
→
down-regulates activity 		SUN1SIGNOR-263281
CDK1phosphorylation
→
down-regulates activity 		SUN1SIGNOR-263099
CDK1phosphorylation
→
down-regulates activity 		SUN1SIGNOR-263100