| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN6 | NFAT5 | Tyr143 | PKRHTVLyISPPPED | dephosphorylation down-regulates activity | 20351292 | SIGNOR-248467 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN6 | dephosphorylation down-regulates ⊣ | NFAT5 PTyr143 | dephosphorylation up-regulates → | NFAT5 | 20351292 | SIGNOR-248467 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN6 | dephosphorylation → down-regulates activity | NFAT5 | SIGNOR-248467 |
