| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EPHB2 | ARHGEF15 | Tyr353 | PLQDEPLyQTYRAAV | phosphorylation down-regulates quantity by destabilization | 21029865 | SIGNOR-262864 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EPHB2 | phosphorylation up-regulates → | ARHGEF15 PTyr353 | phosphorylation down-regulates ⊣ | ARHGEF15 | 21029865 | SIGNOR-262864 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EPHB2 | phosphorylation![]() down-regulates quantity by destabilization | ARHGEF15 | SIGNOR-262864 |