Entity Details

Name CACNA1H
ID O95180
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CAMK2ACACNA1HSer2137RDLRRLYsVDAQGFLphosphorylation
down-regulates activity		38001892SIGNOR-277871
CalcineurinCACNA1HSer2137RDLRRLYsVDAQGFLdephosphorylation
up-regulates activity		38001892SIGNOR-277872
PRKACACACNA1HSer1107LPDSRRGsSSSGDPPphosphorylation
down-regulates activity		19131331SIGNOR-263110
PRKACACACNA1HSer1144AWSSRRSsWSSLGRAphosphorylation
down-regulates activity		19131331SIGNOR-263111
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CAMK2Aphosphorylation
up-regulates
→
CACNA1H
PSer2137		phosphorylation
down-regulates
⊣		CACNA1H38001892SIGNOR-277871
Calcineurindephosphorylation
down-regulates
⊣
CACNA1H
PSer2137		dephosphorylation
down-regulates
⊣		CACNA1H38001892SIGNOR-277872
PRKACAphosphorylation
up-regulates
→
CACNA1H
PSer1107		phosphorylation
down-regulates
⊣		CACNA1H19131331SIGNOR-263110
PRKACAphosphorylation
up-regulates
→
CACNA1H
PSer1144		phosphorylation
down-regulates
⊣		CACNA1H19131331SIGNOR-263111
Regulator Mechanism/Effect Target SIGNOR-ID
CAMK2Aphosphorylation
→
down-regulates activity 		CACNA1HSIGNOR-277871
Calcineurindephosphorylation
→
up-regulates activity 		CACNA1HSIGNOR-277872
PRKACAphosphorylation
→
down-regulates activity 		CACNA1HSIGNOR-263110
PRKACAphosphorylation
→
down-regulates activity 		CACNA1HSIGNOR-263111