| Name | KIF20A |
| ID | O95235 |
| Role | substrate |
| Enzymatic Domains |
Kinesin motor 64-507 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2R5B | KIF20A | Ser878 | RILRSRRsPLLKSGP | dephosphorylation up-regulates activity | 27939310 | SIGNOR-262660 |
| AURKB | KIF20A | Ser878 | RILRSRRsPLLKSGP | phosphorylation down-regulates activity | 27939310 | SIGNOR-262659 |
| PLK1 | KIF20A | – | phosphorylation up-regulates activity | 12939256 | SIGNOR-278201 | |
| NEK6 | KIF20A | Ser244 | LSTSLKRsVYIESRI | phosphorylation down-regulates activity | 28630147 | SIGNOR-273891 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2R5B | dephosphorylation down-regulates ⊣ | KIF20A PSer878 | dephosphorylation down-regulates ⊣ | KIF20A | 27939310 | SIGNOR-262660 |
| AURKB | phosphorylation up-regulates → | KIF20A PSer878 | phosphorylation down-regulates ⊣ | KIF20A | 27939310 | SIGNOR-262659 |
| NEK6 | phosphorylation up-regulates → | KIF20A PSer244 | phosphorylation down-regulates ⊣ | KIF20A | 28630147 | SIGNOR-273891 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2R5B | dephosphorylation → up-regulates activity | KIF20A | SIGNOR-262660 |
| AURKB | phosphorylation → down-regulates activity | KIF20A | SIGNOR-262659 |
| PLK1 | phosphorylation → up-regulates activity | KIF20A | SIGNOR-278201 |
| NEK6 | phosphorylation → down-regulates activity | KIF20A | SIGNOR-273891 |