| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2R5B | KIF20A | Ser878 | RILRSRRsPLLKSGP | dephosphorylation up-regulates activity | 27939310 | SIGNOR-262660 |
| AURKB | KIF20A | Ser878 | RILRSRRsPLLKSGP | phosphorylation down-regulates activity | 27939310 | SIGNOR-262659 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2R5B | dephosphorylation down-regulates ⊣ | KIF20A PSer878 | dephosphorylation down-regulates ⊣ | KIF20A | 27939310 | SIGNOR-262660 |
| AURKB | phosphorylation up-regulates → | KIF20A PSer878 | phosphorylation down-regulates ⊣ | KIF20A | 27939310 | SIGNOR-262659 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPP2R5B | dephosphorylation → up-regulates activity | KIF20A | SIGNOR-262660 |
| AURKB | phosphorylation → down-regulates activity | KIF20A | SIGNOR-262659 |
