Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PLK1	KIF4A	–		phosphorylation down-regulates activity	28817632	SIGNOR-280069
PRKAA1	KIF4A	Ser801 View in OncoXplorer	KLRRRTFsLTEVRGQ	phosphorylation up-regulates activity	28992084	SIGNOR-265991
CyclinB/CDK1	KIF4A	Thr1161 View in OncoXplorer	FFNPVCAtPNSKILK	phosphorylation up-regulates activity	29771379	SIGNOR-265995
AURKB	KIF4A	Thr799 View in OncoXplorer	PPKLRRRtFSLTEVR	phosphorylation up-regulates activity	28992084	SIGNOR-265992
AURKA	KIF4A	Thr799 View in OncoXplorer	PPKLRRRtFSLTEVR	phosphorylation up-regulates activity	31881080	SIGNOR-265993
CDK1	KIF4A	Thr1161 View in OncoXplorer	FFNPVCAtPNSKILK	phosphorylation up-regulates activity	29771379	SIGNOR-265994

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PRKAA1	phosphorylation up-regulates →	KIF4A PSer801	phosphorylation up-regulates →	KIF4A	28992084	SIGNOR-265991
CyclinB/CDK1	phosphorylation up-regulates →	KIF4A PThr1161	phosphorylation up-regulates →	KIF4A	29771379	SIGNOR-265995
AURKB	phosphorylation up-regulates →	KIF4A PThr799	phosphorylation up-regulates →	KIF4A	28992084	SIGNOR-265992
AURKA	phosphorylation up-regulates →	KIF4A PThr799	phosphorylation up-regulates →	KIF4A	31881080	SIGNOR-265993
CDK1	phosphorylation up-regulates →	KIF4A PThr1161	phosphorylation up-regulates →	KIF4A	29771379	SIGNOR-265994

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PLK1	phosphorylation → down-regulates activity	KIF4A	SIGNOR-280069
PRKAA1	phosphorylation → up-regulates activity	KIF4A	SIGNOR-265991
CyclinB/CDK1	phosphorylation → up-regulates activity	KIF4A	SIGNOR-265995
AURKB	phosphorylation → up-regulates activity	KIF4A	SIGNOR-265992
AURKA	phosphorylation → up-regulates activity	KIF4A	SIGNOR-265993
CDK1	phosphorylation → up-regulates activity	KIF4A	SIGNOR-265994